Enzyme-mediated resistance to antibiotics :mechanisms, dissemination, and prospects for inhibition
- au: editors, Robert A. Bonomo, Marcelo Tolmasky.
- Publish: Washington, D.C. : ASM Press c2007.
- 出版年: 2007
- sb: Drug resistance in microorganisms Genetic aspects , Drug resistance in microorganisms , Microbial enzymes , Drug Resistance, Bacterial , antagonists & inhibitors , Genetic aspects , Anti-Bacterial Agents , Enzyme Inhibitors , beta-Lactamases antagonists & inhibitors , beta-Lactamases
- ISBN: 1555813038 , 9781555813031
- ps: Includes bibliographical references and index
- URL: http://www.loc.gov/catdir/toc/ecip078/2007002039.html
- ref_id: 000136733
- type: 圖書
- usertag: 需登入
- 引用網址: 複製連結
There are several mechanisms by which bacteria acquire immunity to antibiotics, but the European and North American scientists here focus on those that are mediated by enzymes. In particular, they look at the enzymatic capabilities of micro-organisms to introduce chemical modifications that negate the biological activity of beta-lactams or aminoglycoside antibiotics. They consider enzymes that defend the bacterial ribosome and cell wall, novel approaches and future prospects for disarming the defense mechanisms, and the dissemination of antibiotic resistance and its biological cost. Annotation 穢2007 Book News, Inc., Portland, OR (booknews.com)